Description

(1R,4E,8E,12S,16R)-4,8,12,14,14-Pentamethyl-13-Oxabicyclo[10.2.2]hexadeca-4,8-dien-16-ol is a high-purity, complex oxabicyclic compound with a defined stereochemistry, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its precise molecular architecture makes it essential for research and development in fine chemical and pharmaceutical applications where stereochemical control is critical. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in oncology, anti-infective, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the design and synthesis of novel, stereochemically-defined pesticides and herbicides.
• Fine Chemical Production: Serves as a sophisticated building block for creating complex fragrance molecules, flavors, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable tool for methodological studies in asymmetric synthesis, catalysis, and total synthesis of natural products.
• Material Science Research: Potential intermediate for developing novel chiral polymers or liquid crystalline materials with specific optical properties.

Basic Information

Product Name	(1R,4E,8E,12S,16R)-4,8,12,14,14-Pentamethyl-13-Oxabicyclo[10.2.2]hexadeca-4,8-dien-16-ol
CAS No.	78039-78-8
Molecular Formula	C20H34O2
Molecular Weight	306.48 g/mol
Synonyms	13-Oxabicyclo[10.2.2]hexadeca-4,8-dien-16-ol, 4,8,12,14,14-pentamethyl-, (1R,4E,8E,12S,16R)-; Ambrosin; (1R,4E,8E,12S,16R)-4,8,12,14,14-Pentamethyl-13-oxabicyclo[10.2.2]hexadeca-4,8-dien-16-ol; (-)-Ambrosin; Ambrosin, (-)-; 78039-78-8; (1R,4E,8E,12S,16R)-rel-4,8,12,14,14-Pentamethyl-13-oxabicyclo[10.2.2]hexadeca-4,8-dien-16-ol
EINECS	Contact for details

Quality Control

Our (1R,4E,8E,12S,16R)-4,8,12,14,14-Pentamethyl-13-Oxabicyclo[10.2.2]hexadeca-4,8-dien-16-ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.