Description

(R)-4-Nitrostyrene Oxide is a high-value chiral epoxide building block with the CAS number 78038-43-4. This optically pure compound is essential for the asymmetric synthesis of complex molecules, offering a critical handle for introducing stereochemistry and functional groups. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for the production of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of bioactive molecules and Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Used in the development of novel, optically active herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Synthesis: Serves as a precursor for creating chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.
• Material Science: Potential monomer or cross-linker for synthesizing polymers with specific optical or mechanical properties.

Basic Information

Product Name	(R)-4-Nitrostyrene Oxide
CAS No.	78038-43-4
Molecular Formula	C8H7NO3
Molecular Weight	165.15 g/mol
Synonyms	(R)-4-Nitro-1,2-epoxyethylbenzene; (R)-1-(4-Nitrophenyl)oxirane; (R)-4-Nitrophenyloxirane; (R)-p-Nitrostyrene Oxide; (R)-4-Nitrostyrene 7,8-oxide; (R)-2-(4-Nitrophenyl)oxirane; (R)-4-NO2-Styrene Oxide; (R)-4-Nitrophenylethylene Oxide
EINECS	Contact for details

Quality Control

Our (R)-4-Nitrostyrene Oxide is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and IR spectroscopy for structural confirmation. Certificates of Analysis (COA) detailing purity, assay, and specific rotation are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.