Description

15-Ketodihydrokaurenoic Acid Methyl Ester is a high-purity, semi-synthetic diterpenoid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial synthetic intermediate and a valuable reference standard for analytical and developmental work. It is primarily utilized by research institutions and industrial R&D departments focused on natural product chemistry, medicinal chemistry, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex diterpenoid analogs and potential drug candidates.
• Reference Standard: Used for method development, validation, and quality control in analytical laboratories (HPLC, GC-MS, NMR).
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new therapeutic pathways.
• Natural Product Synthesis: Serves as a pivotal intermediate in the total or semi-synthesis of kaurene and related diterpenoids.
• Biochemical Research: Used as a probe or substrate in enzymatic studies related to plant hormone biosynthesis and metabolism.

Basic Information

Item	Details
Product Name	15-Ketodihydrokaurenoic Acid Methyl Ester
CAS No.	78037-84-0
Molecular Formula	C₂₁H₃₂O₃
Molecular Weight	332.48 g/mol
Synonyms	Methyl 15-Ketodihydrokaurenoate; 15-Oxodihydrokaur-16-en-19-oic Acid Methyl Ester; 15-Keto-16,17-dihydrokauran-19-oic Acid Methyl Ester; Kaurenoic Acid Derivative; Diterpene Ester; (4aR,5S,6S,8aR)-5,6-Dihydroxy-4a,8a-dimethyl-2-methylidene-3,4,5,6,7,8-hexahydro-1H-naphthalene-1-carboxylic Acid Methyl Ester (related IUPAC forms)
EINECS	Contact for details

Quality Control

Every batch of 15-Ketodihydrokaurenoic Acid Methyl Ester is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.