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11α-Acetoxy-7α,20-Epoxy-6β,7-Dihydroxykaur-16-En-15-One CAS NO 77949-42-9


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CAS No.:77949-42-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

11α-Acetoxy-7α,20-Epoxy-6β,7-Dihydroxykaur-16-En-15-One is a high-purity diterpenoid derivative with a complex, functionalized kaurane skeleton. This compound matters as a critical advanced pharmaceutical intermediate and a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of anti-inflammatory, anti-cancer, and other therapeutic agents, leveraging its unique stereochemistry for targeted drug discovery.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel diterpenoid-based drugs.
  • Medicinal Chemistry Research: Used as a precursor or reference standard in structure-activity relationship (SAR) studies for oncology and immunology targets.
  • Natural Product Synthesis: A valuable intermediate for the semi-synthesis or total synthesis of complex natural products with kaurane backbones.
  • Biochemical Research: Employed in enzymatic studies and as a probe to investigate biological pathways involving diterpenoid metabolism.
  • Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related substances.

Basic Information

Product Name 11α-Acetoxy-7α,20-Epoxy-6β,7-Dihydroxykaur-16-En-15-One
CAS No. 77949-42-9
Molecular Formula C22H30O7
Molecular Weight 406.47 g/mol
Synonyms 11α-Acetoxy-7α,20-epoxy-6β,7-dihydroxykaur-16-en-15-one; 7α,20-Epoxy-6β,7,11α-trihydroxykaur-16-en-15-one 11-acetate; Kaur-16-en-15-one, 11-(acetyloxy)-7,20-epoxy-6,7-dihydroxy-, (6β,7α,11α)-; Ent-11α-Acetoxy-7α,20-epoxy-6β,7-dihydroxykaur-16-en-15-one
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Quality Control

Our 11α-Acetoxy-7α,20-Epoxy-6β,7-Dihydroxykaur-16-En-15-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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