Description

Ethyl L-2-((Trifluoromethylsulfonyl)Oxy)Propionate is a specialized chiral building block and a key intermediate in advanced organic synthesis. Its value lies in the unique reactivity of the triflyloxy (OTf) leaving group, which enables efficient stereospecific nucleophilic substitution reactions under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for constructing complex molecules with defined stereochemistry.

Application

• Pharmaceutical Intermediate: A critical precursor for the synthesis of chiral active pharmaceutical ingredients (APIs), including β-amino acids, peptides, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific herbicides, fungicides, and insecticides where specific chirality is crucial for activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands, organocatalysts, and metal complexes used in asymmetric catalysis.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with tailored properties.
• Custom Synthesis and Process R&D: A valuable reagent for contract research organizations (CROs) and fine chemical companies performing custom synthesis and route scouting.

Basic Information

Product Name	Ethyl L-2-((Trifluoromethylsulfonyl)Oxy)Propionate
CAS No.	77902-90-0
Molecular Formula	C6H9F3O5S
Molecular Weight	250.19 g/mol
Synonyms	Ethyl (2S)-2-[(Trifluoromethyl)sulfonyl]oxypropanoate; (S)-Ethyl 2-(Trifluoromethanesulfonyloxy)propionate; L-2-OTf Propionate Ethyl Ester; Ethyl L-Lactate Triflate; Ethyl (S)-2-((Trifluoromethylsulfonyl)oxy)propanoate; (S)-Ethyl 2-((Trifluoromethylsulfonyl)oxy)propanoate; Ethyl (S)-2-(Triflyloxy)propionate
EINECS	Contact for details

Quality Control

Our Ethyl L-2-((Trifluoromethylsulfonyl)Oxy)Propionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation of quality, especially after the original container is opened. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.