Description

α-Oxo-(3-Cyclohexenyl)Acetic Acid Methyl Ester is a versatile and reactive α-keto ester derivative, serving as a critical chiral building block and synthon in advanced organic synthesis. Its value lies in the reactive ketone and ester functionalities adjacent to the cyclohexenyl ring, enabling a wide range of transformations including asymmetric reductions, nucleophilic additions, and cyclization reactions. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex molecular architectures with high stereochemical control.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized cyclohexane or cyclohexene motifs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials where precise molecular structure is paramount.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including studies on asymmetric catalysis and new reaction pathways.
• Peptidomimetics & Bioactive Molecule Design: The α-keto ester group is a useful scaffold for designing enzyme inhibitors and other bioactive compounds.

Basic Information

Product Name	α-Oxo-(3-Cyclohexenyl)Acetic Acid Methyl Ester
CAS No.	77846-83-4
Molecular Formula	C9H12O3
Molecular Weight	168.19 g/mol
Synonyms	Methyl 2-oxo-2-(3-cyclohexen-1-yl)acetate; 2-(3-Cyclohexen-1-yl)-2-oxoacetic acid methyl ester; (3-Cyclohexen-1-yl)(oxo)acetic acid methyl ester; 3-Cyclohexene-1-glyoxylic acid methyl ester; Methyl (3-cyclohexen-1-yl)oxoacetate; α-Keto-(δ³-cyclohexene)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our α-Oxo-(3-Cyclohexenyl)Acetic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurities is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to moisture and air. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.