Description

(3-Bromo-4-Hydroxyphenyl)(1-Bromo-2-Phenyl-3-Indolizinyl)Methanone is a specialized brominated indolizine derivative that serves as a high-value synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its brominated aromatic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) or charge-transport materials.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition or receptor binding mechanisms.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting cutting-edge synthetic methodology and heterocyclic chemistry research.
• Dye & Pigment Intermediate: Potential starting material for synthesizing specialized dyes and pigments due to its conjugated indolizine core.

Basic Information

Product Name	(3-Bromo-4-Hydroxyphenyl)(1-Bromo-2-Phenyl-3-Indolizinyl)Methanone
CAS No.	77832-81-6
Molecular Formula	C21H13Br2NO2
Molecular Weight	471.14 g/mol
Synonyms	1-Bromo-2-phenyl-3-[(3-bromo-4-hydroxybenzoyl)]indolizine; 3-Bromo-4-hydroxy-1-bromo-2-phenylindolizine ketone; (3-Bromo-4-hydroxyphenyl)(1-bromo-2-phenylindolizin-3-yl)methanone; Methanone, (3-bromo-4-hydroxyphenyl)(1-bromo-2-phenyl-3-indolizinyl)-; 77832-81-6; 1,3-Dibromo-2-phenyl-4-hydroxyindolizine ketone derivative
EINECS	Contact for details

Quality Control

Our (3-Bromo-4-Hydroxyphenyl)(1-Bromo-2-Phenyl-3-Indolizinyl)Methanone is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.