Description

(4Bs)-10α-Acetoxy-4B,5,6,7,8,8Aβ,9,10-Octahydro-3-Hydroxy-4Bα,8,8-Trimethyl-2-Isopropyl-1,4-Phenanthrenedione is a complex, high-purity diterpenoid derivative with a functionalized phenanthrenedione core structure. This compound is valued for its role as a critical advanced intermediate in the synthesis of bioactive molecules, offering a precise chemical scaffold for further functionalization. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams focused on developing novel therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of novel drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in laboratories requiring high-purity compounds for calibration.
• Academic & Institutional Research: Employed in university and research institute settings for studying diterpenoid chemistry, reaction mechanisms, and natural product synthesis.
• Process Chemistry Development: Acts as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material production.
• Biochemical Tool Compound: Utilized in biological assays to investigate specific enzyme interactions or pathway modulations due to its unique structural features.

Basic Information

Product Name	(4Bs)-10α-Acetoxy-4B,5,6,7,8,8Aβ,9,10-Octahydro-3-Hydroxy-4Bα,8,8-Trimethyl-2-Isopropyl-1,4-Phenanthrenedione
CAS No.	77794-82-2
Molecular Formula	C24H34O5
Molecular Weight	402.53 g/mol
Synonyms	10α-Acetoxy-4b,5,6,7,8,8aβ,9,10-octahydro-3-hydroxy-4bα,8,8-trimethyl-2-(1-methylethyl)-1,4-phenanthrenedione; 10-Acetoxy-8,8-dimethyl-2-(propan-2-yl)-4b,5,6,7,8,8a,9,10-octahydro-3-hydroxy-4b-methylphenanthrene-1,4-dione; Abietic acid derivative; Diterpenoid quinone acetate; (4bS)-10α-Acetoxy-4b,5,6,7,8,8aβ,9,10-octahydro-3-hydroxy-4bα,8,8-trimethyl-2-isopropylphenanthrene-1,4-dione
EINECS	Contact for details

Quality Control

Our (4Bs)-10α-Acetoxy-4B,5,6,7,8,8Aβ,9,10-Octahydro-3-Hydroxy-4Bα,8,8-Trimethyl-2-Isopropyl-1,4-Phenanthrenedione is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full characterization data (NMR, MS) is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize the risk of oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.