Description

2-Fluoro-4'-Nitrobenzophenone is a high-purity fluorinated benzophenone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and nitro functional groups, which enable precise modifications to molecular structure and properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Material Research: Acts as a starting material for synthesizing fluorinated organic semiconductors and liquid crystal compounds for electronic displays.
• Polymer Chemistry: Employed in the creation of specialty polymers and advanced materials, where it can be incorporated as a monomer to impart specific thermal or optical properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on cross-coupling reactions, nucleophilic aromatic substitution, and other fluorination chemistry.
• Dye & Pigment Intermediate: Serves as a precursor in the synthesis of complex dyes and pigments, leveraging the nitro group for further functionalization.

Basic Information

Product Name	2-Fluoro-4'-Nitrobenzophenone
CAS No.	77778-85-9
Molecular Formula	C₁₃H₈FNO₃
Molecular Weight	245.21 g/mol
Synonyms	2-Fluoro-4'-nitrobenzophenone; (2-Fluorophenyl)(4-nitrophenyl)methanone; 4'-Nitro-2-fluorobenzophenone; Benzophenone, 2-fluoro-4'-nitro-; 2-Fluoro-4'-nitro-benzophenone; 77778-85-9; Methanone, (2-fluorophenyl)(4-nitrophenyl)-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4'-Nitrobenzophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by IR and NMR, and control of key impurities. Certificates of Analysis (COA) are available for every batch and provided upon request, detailing all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.