Description

Propanoic Acid, 2-[(1,1,2,2,2-Pentafluoroethyl)Thio]- is a specialized organofluorine and organosulfur compound, identified by CAS 77758-95-3. This high-value intermediate is critical for synthesizing advanced materials and active ingredients where the introduction of a pentafluoroethylthio moiety is required. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated thioether groups to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and sulfur atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing novel fluorinated polymers, surface modifiers, and liquid crystals with unique chemical and physical properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories as a specialized reagent for introducing the SC2F5 group into target molecules.
• Ligand and Catalyst Development: Useful in the design of novel ligands and catalysts for transition metal catalysis, leveraging the electronic effects of the fluorine atoms.

Basic Information

Product Name	Propanoic Acid, 2-[(1,1,2,2,2-Pentafluoroethyl)Thio]-
CAS No.	77758-95-3
Molecular Formula	C5H5F5O2S
Molecular Weight	224.15 g/mol
Synonyms	2-[(Pentafluoroethyl)thio]propanoic acid; 2-(Pentafluoroethylthio)propionic acid; α-[(Pentafluoroethyl)thio]propionic acid; 2-(Pentafluoroethanethio)propanoic acid; SC2F5-propanoic acid derivative; Pentafluoroethylthio-propionic Acid; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of Propanoic Acid, 2-[(1,1,2,2,2-Pentafluoroethyl)Thio]- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) including assay (HPLC), identity confirmation (IR, NMR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its sensitivity to strong alkalis and fluorides, keep away from incompatible materials. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.