Description

3-(n-Cbz-Amino)-1-Propanesulfonic Acid CAS NO 77693-74-4 is a specialized sulfonic acid derivative featuring a carboxybenzyl (Cbz) protected amino group, serving as a key building block in organic synthesis and pharmaceutical research. Its value lies in its dual functionality, acting as a protected amine precursor while introducing a strongly acidic sulfonic acid moiety for solubility modification or as a directing group. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel active pharmaceutical ingredients (APIs) and peptide mimetics where controlled introduction of acidity and protected functionality is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those requiring sulfonate groups for enhanced solubility or biological activity.
• Peptide Chemistry: Used in the preparation of modified amino acids and peptide conjugates where the Cbz-protected amine and sulfonic acid group are integral to structure.
• Ligand and Catalyst Synthesis: Employed in the development of specialized ligands for metal catalysis or as an organocatalyst precursor due to its strong acid character.
• Polymer Modification: Acts as a monomer or modifier for introducing sulfonic acid functionality into polymers, potentially for ion-exchange membranes or specialty materials.
• Bioconjugation: Useful in linker chemistry for attaching molecules to surfaces or biomolecules, leveraging the reactive amine (after deprotection) and acid groups.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Item	Details
Product Name	3-(n-Cbz-Amino)-1-Propanesulfonic Acid
CAS No.	77693-74-4
Molecular Formula	C11H15NO5S
Molecular Weight	273.31 g/mol
Synonyms	3-[(Benzyloxycarbonyl)amino]-1-propanesulfonic Acid; N-Cbz-3-Aminopropanesulfonic Acid; 3-(Carbobenzyloxyamino)propanesulfonic Acid; 3-(N-Carbobenzoxyamino)propanesulfonic Acid; 3-Amino-1-propanesulfonic acid N-carboxybenzyl derivative; Z-3-Aminopropanesulfonic Acid; CBZ-APS; N-[(Benzyloxy)carbonyl]-3-aminopropane-1-sulfonic acid
EINECS	Contact for details

Quality Control

Our 3-(n-Cbz-Amino)-1-Propanesulfonic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.