Description

Ent-11,16-Epoxy-15-Hydroxykauran-19-Oic Acid is a high-purity, structurally defined diterpenoid compound of significant interest in advanced chemical synthesis and pharmaceutical research. This specialized kaurene derivative serves as a critical chiral building block and a key intermediate for the development of novel bioactive molecules. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, natural product synthesis, and the exploration of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in oncology and metabolic disease pathways.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Natural Product Synthesis: Serves as a critical intermediate in the total or semi-synthesis of complex diterpenoid natural products and their analogs.
• Biochemical Research: Employed in studies investigating enzyme interactions, biosynthesis pathways, and molecular recognition involving diterpenoid frameworks.
• Reference Standard: Used as an analytical standard in quality control laboratories for the identification and quantification of related compounds.

Basic Information

Product Name	Ent-11,16-Epoxy-15-Hydroxykauran-19-Oic Acid
CAS No.	77658-46-9
Molecular Formula	C₂₀H₂₈O₅
Molecular Weight	348.44 g/mol
Synonyms	(-)-11,16-Epoxy-15-hydroxykauran-19-oic acid; 15-Hydroxy-11,16-epoxykauran-19-oic acid; ent-15-Hydroxy-11β,16-epoxykauran-19-oic acid; Kaurene diterpenoid derivative; 19-Norkaurane-15,19-dioic acid 11,16-ether; 11,16-Epoxy-15-hydroxy-kauran-19-oate; (4aR,5S,6S,8aR,9R,12aR)-5,6-Epoxy-9-hydroxy-4,4a,6,7,8,8a,9,10,11,12-decahydro-3H-5,12a-methanobenzocyclodecen-1(4aH)-one carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our Ent-11,16-Epoxy-15-Hydroxykauran-19-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.