Description

9,9A-Bis(Acetyloxy)-3-[(Acetyloxy)Methyl]-1,1A,1B,4,4A,7A,7B,8,9,9A-Decahydro-4,4A,7B-Trihydroxy-1,1,6,8-Tetramethyl-5H-Cyclopropa[3,4]Benz[1,2-E]Azulen-5-One is a complex, multi-functional diterpenoid derivative of significant interest in advanced organic synthesis. Its intricate polycyclic structure, featuring acetylated hydroxyl groups, makes it a valuable key intermediate for the development of novel bioactive compounds. This high-purity chemical is primarily targeted at pharmaceutical research and development organizations and fine chemical manufacturers engaged in creating specialized molecular libraries.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Chemical Biology Probe Development: Used to create molecular tools for studying biological pathways and target validation.
• Natural Product Analog Synthesis: Acts as a starting material for the semi-synthesis of analogs of complex natural products with diterpenoid backbones.
• Advanced Material Research: Investigated as a precursor for specialty polymers or liquid crystals due to its rigid, functionalized core structure.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in complex molecule construction.

Basic Information

Product Name	9,9A-Bis(Acetyloxy)-3-[(Acetyloxy)Methyl]-1,1A,1B,4,4A,7A,7B,8,9,9A-Decahydro-4,4A,7B-Trihydroxy-1,1,6,8-Tetramethyl-5H-Cyclopropa[3,4]Benz[1,2-E]Azulen-5-One
CAS No.	77646-80-1
Molecular Formula	C27H36O9
Molecular Weight	504.57 g/mol
Synonyms	3-Acetoxymethyl-9,9a-diacetoxy-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4,4a,7b-trihydroxy-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one; 3-(Acetyloxymethyl)-9,9a-bis(acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4,4a,7b-trihydroxy-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one; A derivative of Taxusin; Polyacetylated Taxane Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems (ISO 9001) to ensure batch-to-batch consistency and purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake and potential degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.