Description

(E)-1-(4-Methoxyphenyl)-3-(4-Nitrophenyl)-2-Propene-1-One is a high-purity, specialized chalcone derivative with a defined stereochemistry. This compound is a critical pharmaceutical intermediate and organic synthesis building block, valued for its unique conjugated structure that serves as a core scaffold in medicinal chemistry. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and microbial infections.
• Organic Light-Emitting Diode (OLED) Materials Research: Serves as an electron-transport or emissive layer component due to its extended π-conjugation system.
• Agrochemical Synthesis: Building block for developing new generation pesticides and herbicides with enhanced efficacy.
• Nonlinear Optical (NLO) Materials: Investigated for use in photonic devices and frequency conversion applications owing to its charge-transfer characteristics.
• Chemical Biology Probes: Used in research to study enzyme inhibition and protein-ligand interactions.
• Academic & Industrial R&D: Fundamental research in organic chemistry, heterocyclic compound synthesis, and material science.

Basic Information

Product Name	(E)-1-(4-Methoxyphenyl)-3-(4-Nitrophenyl)-2-Propene-1-One
CAS No.	77636-36-3
Molecular Formula	C16H13NO4
Molecular Weight	283.28 g/mol
Synonyms	(E)-3-(4-Nitrophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one; 4-Methoxy-4'-nitrochalcone; 1-(4-Methoxyphenyl)-3-(4-nitrophenyl)-2-propen-1-one; p-Methoxy-p'-nitrochalcone; (E)-1-(4-Methoxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one; NSC 403914; Chalcone, 4-methoxy-4'-nitro-
EINECS	Contact for details

Quality Control

Our (E)-1-(4-Methoxyphenyl)-3-(4-Nitrophenyl)-2-Propene-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data, including HPLC purity, upon request, supporting compliance with cGMP and ISO standards for research and production use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.