Description

4,4,4-Trifluoro-1-Thiophen-3-Yl-Butane-1,3-Dione is a high-purity fluorinated diketone building block with a thiophene heterocycle. This compound is valued for its unique reactivity profile, serving as a critical intermediate in the synthesis of complex molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for fluorinated ligands, monomers, or functional materials requiring specific electronic properties.
• Chemical Synthesis: A versatile reagent for constructing complex heterocyclic frameworks via condensation or cyclization reactions.
• Academic & Industrial R&D: Employed in discovery chemistry for exploring new reaction pathways and creating compound libraries.

Basic Information

Product Name	4,4,4-Trifluoro-1-Thiophen-3-Yl-Butane-1,3-Dione
CAS No.	77611-51-9
Molecular Formula	C8H5F3O2S
Molecular Weight	222.18 g/mol
Synonyms	3-Thienyl-4,4,4-trifluoro-1,3-butanedione; 4,4,4-Trifluoro-1-(3-thienyl)-1,3-butanedione; 1-(Thiophen-3-yl)-4,4,4-trifluorobutane-1,3-dione; 3-Thienyltrifluoroacetylacetone; TTA; 3-Thenoyltrifluoroacetone (3-TTA); 4,4,4-Trifluoro-1-(thiophen-3-yl)butane-1,3-dione
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-1-Thiophen-3-Yl-Butane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.