Description

5-Chloro-2,2,3,3,4-Pentafluoropent-4-Enoic Acid is a high-value, multi-functional fluorinated organic acid building block. Its unique structure, featuring both a reactive carboxylic acid group and a chloro-pentafluoroalkene moiety, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for R&D and production in the pharmaceutical, agrochemical, and specialty polymer industries seeking to incorporate fluorinated segments for enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel fluorinated active pharmaceutical ingredients (APIs) and prodrugs, leveraging fluorine's metabolic stability and bioavailability benefits.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and pesticides where the fluorinated chain improves lipophilicity, membrane permeability, and environmental persistence.
• Specialty Polymer & Material Science: Serves as a monomer or modifier for producing fluorinated polymers, coatings, and surfactants with superior chemical resistance, thermal stability, and low surface energy.
• Liquid Crystal & Electronic Materials: A precursor for fluorinated liquid crystal compounds and organic electronic materials used in displays and semiconductor applications.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis due to its electron-withdrawing fluorinated alkene group.
• Research & Development: A valuable tool for medicinal chemistry and material science research exploring structure-activity relationships (SAR) of fluorinated compounds.

Basic Information

Product Name	5-Chloro-2,2,3,3,4-Pentafluoropent-4-Enoic Acid
CAS No.	77569-70-1
Molecular Formula	C5H2ClF5O2
Molecular Weight	224.51 g/mol
Synonyms	5-Chloro-2,2,3,3,4-pentafluoro-4-pentenoic acid; 4-Pentenoic acid, 5-chloro-2,2,3,3,4-pentafluoro-; 5-Chloro-2,2,3,3,4-pentafluoropent-4-enoic acid; Pentafluoropentenoic acid, chloro derivative; 5-Chloro-pentafluoropent-4-enoic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,2,3,3,4-Pentafluoropent-4-Enoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistent quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.