Description

2-Bromomethyl-3-Chlorobenzonitrile is a versatile and high-value halogenated aromatic building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate for introducing functionalized benzyl groups. It is essential for research and development chemists and production-scale manufacturers engaged in creating active pharmaceutical ingredients (APIs), advanced crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its reactive bromomethyl and nitrile groups.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organic synthesis.
• Material Science Research: Employed in the synthesis of monomers and functionalized polymers with specific electronic or structural properties.
• Custom Synthesis and Contract Manufacturing: A key raw material for fine chemical companies offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-Bromomethyl-3-Chlorobenzonitrile
CAS No.	77533-18-7
Molecular Formula	C8H5BrClN
Molecular Weight	230.49 g/mol
Synonyms	3-Chloro-2-(bromomethyl)benzonitrile; 2-(Bromomethyl)-3-chlorobenzonitrile; 3-Chloro-2-bromomethylbenzonitrile; 2-Bromomethyl-3-chlorobenzonitrile; Benzonitrile, 3-chloro-2-(bromomethyl)-; (3-Chloro-2-cyanophenyl)methyl bromide
EINECS	Contact for details

Quality Control

Our 2-Bromomethyl-3-Chlorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming identity, assay, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.