Description

2-Bromo-6-Methylbenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and nitrile functional groups, makes it a critical intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the bromine atom serves as a handle for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers due to its rigid aromatic core and reactive sites.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying biological pathways and protein functions.

Basic Information

Item	Detail
Product Name	2-Bromo-6-Methylbenzonitrile
CAS No.	77532-87-7
Molecular Formula	C8H6BrN
Molecular Weight	196.05 g/mol
Synonyms	2-Bromo-6-methylbenzonitrile; 6-Methyl-2-bromobenzonitrile; 2-Bromo-o-tolunitrile; o-Tolunitrile, 2-bromo-; Benzonitrile, 2-bromo-6-methyl-; (2-Bromo-6-methylphenyl)cyanide; 2-Bromo-6-tolunitrile; 77532-87-7
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Methylbenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.