Description

1,4,5,5,6,6-Hexafluoro-2,3-Dimethoxybicyclo[2.2.0]Hex-2-Ene is a highly specialized fluorinated bicyclic compound, valued for its unique structural framework and reactivity. This chemical serves as a critical advanced intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, specialty polymers, and high-performance materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, especially those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the fluorinated bicyclic structure can contribute to improved efficacy and environmental profile.
• Advanced Material Science: Serves as a precursor for specialty polymers, liquid crystals, and other high-performance materials that benefit from its rigid, fluorinated core.
• Organic Synthesis & Catalysis: Employed in academic and industrial research as a unique dienophile or ligand precursor in catalytic cycles and cycloaddition reactions.
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships and developing new fluorination methodologies.

Basic Information

Product Name	1,4,5,5,6,6-Hexafluoro-2,3-Dimethoxybicyclo[2.2.0]Hex-2-Ene
CAS No.	77495-74-0
Molecular Formula	C8H6F6O2
Molecular Weight	248.12 g/mol
Synonyms	Hexafluorodimethoxybicyclo[2.2.0]hex-2-ene; 1,4,5,5,6,6-Hexafluoro-2,3-dimethoxybicyclo[2.2.0]hex-2-ene; Bicyclo[2.2.0]hex-2-ene, 1,4,5,5,6,6-hexafluoro-2,3-dimethoxy-; 2,3-Dimethoxy-1,4,5,5,6,6-hexafluorobicyclo[2.2.0]hex-2-ene
EINECS	Contact for details

Quality Control

Every batch of 1,4,5,5,6,6-Hexafluoro-2,3-Dimethoxybicyclo[2.2.0]Hex-2-Ene is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC/GC), impurity profile, and spectroscopic identification are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥95.0% (Typical 97-99%)
Purity (by NMR)	Conforms
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.