Description

Gonyautoxins are a group of potent neurotoxins primarily produced by marine dinoflagellates, with the specific compound referenced as CAS NO 77462-64-7. These saxitoxin analogues are critical for research into paralytic shellfish poisoning (PSP) and the development of detection methods to ensure seafood safety. This high-purity reference material is essential for analytical laboratories, toxicology researchers, and regulatory bodies focused on marine biotoxin monitoring and neurological studies.

Application

• Reference Standard for Analytical Testing: Primary calibration standard for the accurate quantification of paralytic shellfish toxins (PSTs) in seafood and water samples via HPLC, LC-MS/MS, or mouse bioassay methods.
• Toxicological Research: Used in studies to understand the mechanism of action of saxitoxin analogues on voltage-gated sodium channels and their neurotoxic effects.
• Diagnostic Kit Development: Serves as a key antigen or standard in the development and validation of immunoassays, biosensors, and rapid test kits for PSP detection.
• Pharmaceutical & Biomedical Research: Investigated for its potential in neurological studies and as a tool for probing ion channel function.
• Environmental Monitoring & Regulatory Compliance: Employed by government and environmental agencies to monitor algal blooms and enforce shellfish safety regulations.
• Food Safety & Quality Control: Critical for in-house quality control laboratories in the seafood industry to validate testing procedures and ensure product safety.

Basic Information

Product Name	Gonyautoxins
CAS No.	77462-64-7
Molecular Formula	C10H17N7O4
Molecular Weight	299.29 g/mol
Synonyms	GTX5; Gonyautoxin V; 11-Hydroxysaxitoxin sulfate; 11α-Hydroxysaxitoxin 21-O-sulfate; Decarbamoylgonyautoxin 5; N-sulfocarbamoyl-11-hydroxysaxitoxin; Paralytic Shellfish Poison GTX5; (3aS,4R,9aS)-2,6-Diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-1H,7H-pyrrolo[1,2-c]purine-7,9,10(2H)-trione 10-sulfate
EINECS	Contact for details

Quality Control

Our Gonyautoxins (CAS 77462-64-7) is manufactured and handled under strict quality protocols suitable for analytical and research use. Each batch undergoes comprehensive analysis using advanced techniques like HPLC and mass spectrometry to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided, documenting critical parameters such as assay purity and impurity profile to ensure reliability and traceability for your research and regulatory applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Assay (HPLC)	≥95% (Area Percent)
Water Content (KF)	≤5.0%
Related Substances (HPLC)	Individual impurity ≤2.0%
Solubility	Soluble in water, aqueous acidic solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.