Description

5-Chloro-4-(4-Fluorophenyl)-1,2,3-Thiadiazole is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring a thiadiazole core with chloro and fluorophenyl substituents, makes it a critical intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used as a building block for the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Material Science Research: Investigated as a precursor for specialty chemicals and functional materials, such as ligands for catalysis or components in electronic materials.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-Chloro-4-(4-Fluorophenyl)-1,2,3-Thiadiazole
CAS No.	77414-44-9
Molecular Formula	C8H4ClFN2S
Molecular Weight	214.64 g/mol
Synonyms	5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole; 4-(4-Fluorophenyl)-5-chloro-1,2,3-thiadiazole; 5-Chloro-4-(p-fluorophenyl)-1,2,3-thiadiazole; 1,2,3-Thiadiazole, 5-chloro-4-(4-fluorophenyl)-; 77414-44-9; 5-Chloro-4-(4-fluorophenyl)-[1,2,3]thiadiazole
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-(4-Fluorophenyl)-1,2,3-Thiadiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), physical characteristics, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.