Description

4-(4-Fluoro-Phenyl)-Cyclohexanol is a versatile fluorinated cyclohexanol derivative that serves as a critical chiral intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and liquid crystal materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemicals sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials for OLED devices.
• Asymmetric Catalysis Research: Valuable substrate or ligand precursor in the study and development of new asymmetric catalytic reactions.
• Fine Chemical Production: Intermediate for the synthesis of other specialty fluorinated compounds used in various high-value chemical applications.

Basic Information

Product Name	4-(4-Fluoro-Phenyl)-Cyclohexanol
CAS No.	77412-73-8
Molecular Formula	C12H15FO
Molecular Weight	194.25 g/mol
Synonyms	4-(4-Fluorophenyl)cyclohexanol; trans-4-(4-Fluorophenyl)cyclohexanol; 4-(p-Fluorophenyl)cyclohexanol; 4-Cyclohexanol, 4-(4-fluorophenyl)-; 4-(4-Fluorophenyl)-1-cyclohexanol; 4-(4-Fluorophenyl)cyclohexan-1-ol; 4-Fluorophenylcyclohexanol
EINECS	Contact for details

Quality Control

Our 4-(4-Fluoro-Phenyl)-Cyclohexanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, and we support compliance with cGMP, ISO, and REACH regulations as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (specify isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.