Description

(3R,5R)-(-)-3,5-Heptanediol CAS NO 77291-90-8 is a high-purity chiral diol building block of significant importance in asymmetric synthesis and pharmaceutical chemistry. Its defined stereochemistry makes it a valuable precursor for the production of complex molecules, particularly in the synthesis of chiral drugs, agrochemicals, and specialty polymers. This compound is essential for research institutions and industrial manufacturers requiring enantiomerically pure intermediates for advanced chemical development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in statin-type drugs and other therapeutics requiring specific stereocenters.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where biological activity is often stereospecific.
• Ligand and Catalyst Development: Serves as a backbone for constructing chiral ligands and organocatalysts used in asymmetric catalytic reactions.
• Specialty Polymer Monomer: Employed in the synthesis of chiral polymers and polyesters with unique optical or material properties.
• Flavor and Fragrance Ingredient: Acts as a precursor for chiral aroma chemicals and flavor compounds.
• Academic and R&D: A valuable reagent for methodological development in organic synthesis and stereochemistry research.

Basic Information

Product Name	(3R,5R)-(-)-3,5-Heptanediol
CAS No.	77291-90-8
Molecular Formula	C7H16O2
Molecular Weight	132.20 g/mol
Synonyms	(3R,5R)-3,5-Heptanediol; (3R,5R)-Heptane-3,5-diol; (-)-3,5-Heptanediol; (R,R)-(-)-3,5-Heptanediol; (3R,5R)-(-)-Heptanediol; 3,5-Heptanediol, (3R,5R)-(-)-; (3R-cis)-3,5-Heptanediol
EINECS	Contact for details

Quality Control

Our (3R,5R)-(-)-3,5-Heptanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC and optical rotation measurement, to ensure compliance with customer specifications and high industry standards. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Optical Rotation [α]20/D	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.