Description

2-Iodo-5-Methoxybenzaldehyde is a versatile halogenated aromatic aldehyde that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an electron-donating methoxy group and a reactive iodo substituent, makes it an invaluable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and plant growth regulators requiring specific halogenated aromatic cores.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoactive polymers.
• Chemical Research & Development: A valuable reagent for method development in organic synthesis, including Suzuki-Miyaura and other palladium-catalyzed cross-couplings.
• Fine Chemical Production: Intermediate for the manufacture of dyes, pigments, and other specialty chemicals requiring a substituted benzaldehyde framework.

Basic Information

Product Name	2-Iodo-5-Methoxybenzaldehyde
CAS No.	77287-58-2
Molecular Formula	C8H7IO2
Molecular Weight	262.05 g/mol
Synonyms	5-Methoxy-2-iodobenzaldehyde; 2-Iodo-5-methoxybenzaldehyde; 5-Methoxy-2-iodobenzenecarboxaldehyde; 2-Iodo-5-anisaldehyde; 5-Methoxy-o-iodobenzaldehyde; o-Iodo-5-methoxybenzaldehyde; Benzaldehyde, 2-iodo-5-methoxy-
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for 2-Iodo-5-Methoxybenzaldehyde to ensure batch-to-batch consistency and high purity. Our standard material typically meets a purity specification of ≥97% (by HPLC), suitable for research and development applications. For specific project requirements, including higher purity grades (≥98% or ≥99%), please contact our technical sales team. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.