Description

Desacetylscalaradial is a bioactive scalarane-type sesterterpenoid, a derivative of the natural marine product scalaradial. This compound is valued for its role as a key intermediate and reference standard in pharmaceutical and biochemical research, particularly in studies of inflammation and enzyme inhibition. It is essential for researchers and manufacturers in the life sciences sector developing novel therapeutic agents or analytical methods.

Application

• Pharmaceutical Research Intermediate: Serves as a critical precursor in the synthesis of novel anti-inflammatory and anti-cancer agents targeting phospholipase A2 (PLA2).
• Biochemical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in HPLC and LC-MS assays.
• Mechanistic Studies: Employed in in vitro and ex vivo research to investigate the role of secretory PLA2 in inflammatory pathways and signal transduction.
• Natural Product Chemistry: A valuable compound for the study of marine-derived sesterterpenoids, their structure-activity relationships, and synthetic analogs.
• High-Value Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized bioactive molecules for preclinical development.

Basic Information

Product Name	Desacetylscalaradial
CAS No.	77282-60-1
Molecular Formula	C25H36O4
Molecular Weight	400.56 g/mol
Synonyms	12-Deacetyl-12-oxoscalaradial; 12-Deoxyscalaradial; Nor-12-acetyl scalaradial; Scalaradial derivative; (4E,6E,8E,12E,14E,18R)-18-Hydroxy-4,8,13,17-tetramethyl-20-oxo-3,16-dioxapentacyclo[12.4.0.02,11.05,10.015,19]octadeca-1(14),2(11),4,6,8,12,15(19)-heptaene-7-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of Desacetylscalaradial is manufactured and controlled under a strict quality management system. We provide comprehensive analytical documentation to support research and regulatory requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments, ensuring traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.