Description

(2R)-2-Hydroxy-Hexanedioic Acid is a high-purity chiral building block and intermediate of significant value in fine chemical synthesis. Its stereochemical purity makes it a critical component for producing optically active compounds where specific molecular handedness is required. This product is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for applications involving chiral resolution and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of enantiomerically pure drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereoisomer can affect biological activity and environmental safety.
• Fine Chemical Manufacturing: Serves as a versatile building block for creating complex molecules in flavors, fragrances, and advanced materials.
• Biochemical Research: Employed in enzymatic studies and as a precursor for synthesizing chiral ligands and catalysts used in asymmetric catalysis.
• Polymer Modification: Can be used to introduce chiral centers into polymer chains, potentially altering material properties for specialized applications.

Basic Information

Product Name	(2R)-2-Hydroxy-Hexanedioic Acid
CAS No.	77252-44-9
Molecular Formula	C6H10O5
Molecular Weight	162.14 g/mol
Synonyms	(R)-2-Hydroxyhexanedioic acid; (R)-2-Hydroxyadipic acid; D-2-Hydroxyadipic acid; (2R)-2-Hydroxyadipic acid; (R)-α-Hydroxyadipic acid; (R)-2-Hydroxy-1,6-hexanedioic acid; (R)-2-Hydroxyhexane-1,6-dioic acid
EINECS	Contact for details

Quality Control

Our (2R)-2-Hydroxy-Hexanedioic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including HPLC for chiral purity and standard identity confirmation tests. A Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is supplied with each batch to meet the stringent requirements of our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.