Description

4-(Trimethylsilyl)Ethynylbenzaldehyde is a specialized organosilicon building block featuring a reactive aldehyde group and a protected ethynyl moiety. This compound is valued for its dual functionality, enabling its use in advanced organic synthesis and materials science. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring alkyne and aldehyde coupling reactions.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where its functional groups allow for the creation of diverse chemical structures.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, dendrimers, and organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis and organometallic complexes.
• Chemical Biology Probes: Utilized in click chemistry and bioconjugation strategies to label biomolecules or create molecular probes.
• Academic & Industrial R&D: A versatile reagent for exploratory organic synthesis in research and development laboratories.

Basic Information

Product Name	4-(Trimethylsilyl)Ethynylbenzaldehyde
CAS No.	77123-57-0
Molecular Formula	C₁₂H₁₄OSi
Molecular Weight	202.33 g/mol
Synonyms	4-((Trimethylsilyl)ethynyl)benzaldehyde; 4-(Trimethylsilylethynyl)benzaldehyde; p-(Trimethylsilylethynyl)benzaldehyde; Benzaldehyde, 4-[(trimethylsilyl)ethynyl]-; 4-Ethynylbenzaldehyde trimethylsilyl ether; TMS-Ethynylbenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-(Trimethylsilyl)Ethynylbenzaldehyde is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.