Description

3-Fluoro-Propionaldehyde is a versatile fluorinated aldehyde building block of significant interest in advanced organic synthesis. Its value lies in the introduction of a fluorine atom and an aldehyde functional group, enabling precise molecular modifications to enhance the properties of target compounds. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), where fluorine can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that benefit from the unique properties of fluorine-containing molecules.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized fluorinated ligands used in asymmetric catalysis and material science.
• Fluorinated Polymer Research: An important monomer or modifier in the development of specialty polymers with enhanced chemical resistance or surface properties.
• Organic Synthesis Reagent: Employed in various name reactions, such as aldol condensations and reductive aminations, to introduce fluorinated segments.
• Fluorine Chemistry Research: A valuable tool in academic and industrial labs for studying structure-activity relationships (SAR) and new fluorination methodologies.

Basic Information

Product Name	3-Fluoro-Propionaldehyde
CAS No.	77063-66-2
Molecular Formula	C₃H₅FO
Molecular Weight	76.07 g/mol
Synonyms	3-Fluoropropanal; 3-Fluoropropionaldehyde; β-Fluoropropionaldehyde; 3-Fluoropropaldehyde; 3-Fluoro-1-propanal; 3-Fluoropropane-1-al; 77063-66-2; Propionaldehyde, 3-fluoro-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-Propionaldehyde is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific project requirements, supporting compliance in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) in a cool, well-ventilated place. Due to its highly volatile and easily oxidized nature, it is recommended to store at 2-8°C for extended stability. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.