Description

2-Amino-3-Biphenyl-4-Yl-Propionic Acid is a specialized non-proteinogenic amino acid derivative featuring a biphenyl moiety. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), peptide mimetics, and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially those targeting neurological or inflammatory pathways.
• Peptidomimetics Research: Used to incorporate biphenyl groups into peptide backbones to enhance stability, bioavailability, and receptor binding affinity.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in stereoselective transformations.
• Biochemical Research: Utilized in studies exploring enzyme inhibition or as a non-natural amino acid analog in biochemical assays.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-Amino-3-Biphenyl-4-Yl-Propionic Acid
CAS No.	76985-08-5
Molecular Formula	C₁₅H₁₅NO₂
Molecular Weight	241.29 g/mol
Synonyms	2-Amino-3-(4-biphenylyl)propanoic acid; DL-2-Amino-3-(biphenyl-4-yl)propionic acid; 3-(4-Phenylphenyl)-DL-alanine; 4-Biphenylalanine; Biphenyl-4-yl-alanine; (RS)-2-Amino-3-(biphenyl-4-yl)propanoic acid; 2-Amino-3-([1,1'-biphenyl]-4-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Biphenyl-4-Yl-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets rigorous R&D and process development standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.