Description

2-Ethynyloxolane is a versatile heterocyclic building block featuring an oxolane (tetrahydrofuran) ring substituted with an ethynyl group. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is particularly sought after by pharmaceutical and agrochemical companies for creating novel active ingredients and by material scientists developing specialty polymers and ligands.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers with tailored thermal or mechanical properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new organic reactions and constructing complex molecular architectures.
• Fine Chemical Production: Intermediate in the multi-step synthesis of high-value, low-volume specialty chemicals.

Basic Information

Product Name	2-Ethynyloxolane
CAS No.	76928-54-6
Molecular Formula	C6H8O
Molecular Weight	96.13 g/mol
Synonyms	2-Ethynyltetrahydrofuran; 2-Ethynyloxacyclopentane; 2-Ethynyl-THF; Tetrahydro-2-furanylethyne; 2-(Ethynyl)oxolane; 2-Ethynyltetrahydrofuran-; Oxolane, 2-ethynyl-
EINECS	Contact for details

Quality Control

Every batch of 2-Ethynyloxolane is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets your specific research or production requirements. A detailed Certificate of Analysis (COA) including purity (typically by GC or HPLC), identity confirmation (IR, NMR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, keep containers tightly sealed when not in use and away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.