Description

2',5'-Bis(2,2,2-Trifluoroethoxy)Acetophenone is a high-purity fluorinated aromatic ketone building block, identified by CAS number 76784-40-2. This compound is valued for its unique trifluoroethoxy substituents, which impart significant electronic and lipophilic properties, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas where fluorine substitution is beneficial.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the trifluoroethoxy groups to enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), where its structure aids in tuning electronic properties.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and the creation of novel fluorinated compound libraries.

Basic Information

Product Name	2',5'-Bis(2,2,2-Trifluoroethoxy)Acetophenone
CAS No.	76784-40-2
Molecular Formula	C12H10F6O3
Molecular Weight	316.20 g/mol
Synonyms	1-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]ethanone; 2',5'-Di(2,2,2-trifluoroethoxy)acetophenone; 2,5-Bis(2,2,2-trifluoroethoxy)acetophenone; Acetophenone, 2',5'-bis(2,2,2-trifluoroethoxy)-; Ethanone, 1-[2,5-bis(2,2,2-trifluoroethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 2',5'-Bis(2,2,2-Trifluoroethoxy)Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.