Description

Pyrazolo[5,1-B]Quinazoline-2-Carboxylic Acid, 4,9-Dihydro-5,7-Dimethoxy-9-Oxo- is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical advanced pharmaceutical intermediate (API intermediate). Its value lies in its complex fused-ring structure, which is essential for synthesizing novel bioactive compounds with targeted therapeutic effects. This product is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly for applications in medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic frameworks in academic and industrial R&D laboratories.
• Biochemical Reagent: Potential use as a reference standard or a specialized reagent in biochemical assays and screening libraries.

Basic Information

Product Name	Pyrazolo[5,1-B]Quinazoline-2-Carboxylic Acid, 4,9-Dihydro-5,7-Dimethoxy-9-Oxo-
CAS No.	76745-64-7
Molecular Formula	C₁₄H₁₃N₃O₅
Molecular Weight	303.27 g/mol
Synonyms	4,9-Dihydro-5,7-dimethoxy-9-oxopyrazolo[5,1-b]quinazoline-2-carboxylic acid; Pyrazolo[5,1-b]quinazoline-2-carboxylic acid, 4,9-dihydro-5,7-dimethoxy-9-oxo-; 5,7-Dimethoxy-9-oxo-4,9-dihydropyrazolo[5,1-b]quinazoline-2-carboxylic acid; 76745-64-7; UNII-9Q8VW3Z0Q5; 9Q8VW3Z0Q5; SCHEMBL218430; DTXSID90654269
EINECS	Contact for details

Quality Control

Our Pyrazolo[5,1-B]Quinazoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.