Description

5-(m-(Trifluoromethyl)Benzylidene)Hydantoin is a specialized heterocyclic organic compound featuring a hydantoin core substituted with a trifluoromethylbenzylidene group. This molecular architecture makes it a valuable intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs), particularly where the introduction of fluorine atoms is desired to modulate biological activity and physicochemical properties. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors for development and production processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the trifluoromethyl group.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, where the hydantoin moiety can contribute to specific biological activity.
• Material Science Research: Serves as a precursor for creating specialized polymers and liquid crystals, where its rigid structure and fluorine content can influence thermal stability and optical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated heterocycles for client-specific applications.

Basic Information

Product Name	5-(m-(Trifluoromethyl)Benzylidene)Hydantoin
CAS No.	76605-42-0
Molecular Formula	C11H7F3N2O2
Molecular Weight	256.18 g/mol
Synonyms	5-[(3-(Trifluoromethyl)phenyl)methylene]-2,4-imidazolidinedione; 5-(3-Trifluoromethylbenzylidene)hydantoin; 3-(3-Trifluoromethylbenzylidene)-2,4(3H,5H)-imidazoledione; (3-Trifluoromethylbenzylidene)hydantoin; m-Trifluoromethylbenzylidene hydantoin; 5-(m-Trifluoromethylbenzylidene)-2,4-imidazolidinedione; 76605-42-0; Hydantoin, 5-[(3-(trifluoromethyl)phenyl)methylene]-
EINECS	Contact for details

Quality Control

Our 5-(m-(Trifluoromethyl)Benzylidene)Hydantoin is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for research and industrial use. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.