Description

8-Acetoxy-15,16-Epoxy-8,9-Secolabda-13(16),14-Diene-7,9-Dione is a high-purity, specialized diterpenoid derivative with a complex, functionalized secolabdane skeleton. This compound serves as a critical advanced intermediate for the synthesis of novel bioactive molecules and complex natural product analogs. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel diterpenoid-based drug candidates targeting inflammation, cancer, and infectious diseases.
• Medicinal Chemistry Research: Used in lead optimization and SAR studies to explore new chemical space and biological activity.
• Natural Product Synthesis: Serves as a sophisticated precursor in the total or semi-synthesis of complex labdane-type natural products.
• Biochemical Probes: Potential use in developing molecular probes to study specific enzyme interactions or biological pathways.
• Reference Standard: High-purity material for use as an analytical standard in quality control and method development for related compounds.

Basic Information

Product Name	8-Acetoxy-15,16-Epoxy-8,9-Secolabda-13(16),14-Diene-7,9-Dione
CAS No.	76475-32-6
Molecular Formula	C22H28O5
Molecular Weight	372.46 g/mol
Synonyms	8α-Acetoxy-15,16-epoxy-8,9-secolabda-13(16),14-diene-7,9-dione; 8-Acetoxy-15,16-epoxy-8,9-secolabdane-13(16),14-diene-7,9-dione; Secolabdane diterpenoid acetate; (4aR,5S,6aS,9R,9aR,9bS)-9-Acetyloxy-5-(3-furyl)-4a,6a-dimethyl-3,4,5,6,6a,7,8,9,9a,9b-decahydro-2H-naphtho[1,2-b]furan-2-one
EINECS	Contact for details

Quality Control

Every batch of 8-Acetoxy-15,16-Epoxy-8,9-Secolabda-13(16),14-Diene-7,9-Dione is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.