Description

α-Monofluoromethyl-β-(2,3-Dihydroxyphenyl)Alanine is a specialized fluorinated amino acid derivative with a unique dihydroxyphenyl side chain. This compound is a critical chiral building block and intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly for applications in neurology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the synthesis of potential drug candidates targeting neurotransmitter pathways and neurological disorders.
• Enzyme Inhibitor Studies: Serves as a precursor for designing mechanism-based enzyme inhibitors due to its fluoromethyl and catechol functionalities.
• Metabolic Disease Research: Employed in developing compounds for research into metabolic pathways and related therapeutic areas.
• Asymmetric Synthesis: Valuable building block in stereoselective organic synthesis for introducing fluorinated amino acid motifs.
• Biochemical Probe Development: Used to create labeled or modified probes for studying biological processes and protein interactions.

Basic Information

Product Name	α-Monofluoromethyl-β-(2,3-Dihydroxyphenyl)Alanine
CAS No.	76409-26-2
Molecular Formula	C11H14FNO4
Molecular Weight	243.23 g/mol
Synonyms	2-Amino-3-(2,3-dihydroxyphenyl)-2-fluoropropanoic acid; (2R,3S)-2-Amino-3-(2,3-dihydroxyphenyl)-2-fluoropropanoic acid; L-α-(Fluoromethyl)-3,4-dihydroxyphenylalanine; Fluoromethyl-DOPA; 2-Fluoro-3-(2,3-dihydroxyphenyl)alanine; FMDOPA; (S)-2-Amino-2-fluoromethyl-3-(2,3-dihydroxyphenyl)propionic acid
EINECS	Contact for details

Quality Control

Our α-Monofluoromethyl-β-(2,3-Dihydroxyphenyl)Alanine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.