Description

2-Isopropylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it ideal for handling, storage, and use in demanding synthetic sequences. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-purity intermediates for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling, enabling the formation of critical carbon-carbon bonds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific biaryl or alkyl-aryl structures.
• Material Science Research: Serves as a monomer or building block for creating advanced organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Chemical Biology & Medicinal Chemistry: Employed in the discovery and optimization of drug candidates, particularly in fragment-based drug design and library synthesis.
• Catalyst & Ligand Development: Acts as a precursor for synthesizing novel organoboron-based catalysts and ligands used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing complex, boron-containing molecules for client projects.

Basic Information

Product Name	2-Isopropylboronic Acid, Pinacol Ester
CAS No.	76347-13-2
Molecular Formula	C11H23BO2
Molecular Weight	198.11 g/mol
Synonyms	2-Isopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Isopropyl-1,3,2-dioxaborolan-4,4,5,5-tetramethyl); Pinacol (2-Isopropyl)boronate; 2-Isopropylboronic Acid Pinacol Ester; Isopropylboronic Acid Pinacol Ester; 2-Propaneboronic Acid, Pinacol Ester; (Isopropyl)Pinacolborane; B-Isopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Isopropylboronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC or HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.