Description

D-Alanine, 3-Fluoro-n-Glycyl- (9Ci) CAS NO 76312-86-2 is a specialized, non-natural amino acid derivative featuring a fluorine atom and a glycyl moiety, designed for advanced research and development. This high-purity building block is critical for medicinal chemists and peptide researchers seeking to modulate the biological activity, metabolic stability, and physicochemical properties of novel compounds. It is primarily utilized in pharmaceutical R&D for the synthesis of fluorinated peptides and peptidomimetics, as well as in agrochemical discovery and as a biochemical tool in life sciences.

Application

• Pharmaceutical Intermediate: A key fluorinated building block for the synthesis of novel peptide-based drug candidates, including protease inhibitors and GPCR-targeting therapeutics.
• Medicinal Chemistry Research: Used to introduce fluorine into peptide backbones to enhance metabolic stability, membrane permeability, and binding affinity in structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a precursor in the research and synthesis of advanced, fluorinated bioactive compounds for crop protection.
• Biochemical Probe Synthesis: Employed in creating labeled or modified peptides for studying enzyme mechanisms, protein-protein interactions, and cellular pathways.
• Peptide Library Construction: An essential component for generating diverse peptide libraries in combinatorial chemistry for high-throughput screening.
• Academic & Institutional Research: Used in universities and research institutes for fundamental studies in organic synthesis, fluorine chemistry, and peptide science.

Basic Information

Product Name	D-Alanine, 3-Fluoro-n-Glycyl- (9Ci)
CAS No.	76312-86-2
Molecular Formula	C5H9FN2O3
Molecular Weight	164.14 g/mol
Synonyms	3-Fluoro-N-glycyl-D-alanine; D-3-Fluoronoglycylanine; N-(2-Aminoacetyl)-3-fluoro-D-alanine; Glycine, N-(3-fluoro-D-alanyl)-; (R)-2-((2-Aminoacetamido)-3-fluoropropanoic acid; 3-Fluoro-D-alanylglycine; Fluorinated D-Ala-Gly dipeptide analog
EINECS	Contact for details

Quality Control

Our D-Alanine, 3-Fluoro-n-Glycyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.