Description

1-(Bromomethyl)-4-Chloro-2-Methoxybenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its reactive bromomethyl and chloro substituents make it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in drug discovery, material science, and the synthesis of specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring substituted benzyl or aryl ether motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce functionalized benzyl groups.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Dye and Pigment Intermediate: Used in the synthesis of complex organic dyes and pigments.

Basic Information

Product Name	1-(Bromomethyl)-4-Chloro-2-Methoxybenzene
CAS No.	76283-12-0
Molecular Formula	C8H8BrClO
Molecular Weight	235.51 g/mol
Synonyms	4-Chloro-2-methoxybenzyl bromide; 2-Methoxy-4-chlorobenzyl bromide; (4-Chloro-2-methoxyphenyl)methyl bromide; 1-Bromomethyl-4-chloro-2-methoxybenzene; 4-Chloro-2-methoxy-α-bromotoluene; α-Bromo-4-chloro-2-methoxy toluene; p-Chloro-o-methoxybenzyl bromide
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-4-Chloro-2-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.