Description

2,2-Dimethyl-Propionic Acid (1R,5R)-6,6-Dimethyl-4-Oxo-Bicyclo[3.1.1]Hept-2-En-2-Ylmethyl Ester is a high-purity, chiral bicyclic ester building block of significant interest in advanced organic synthesis. Its unique, rigid molecular framework makes it a valuable precursor for constructing complex, stereodefined structures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly those requiring complex, polycyclic architectures.
• Agrochemical Synthesis: Used in the creation of advanced, biologically active molecules for crop protection and pest management solutions.
• Asymmetric Catalysis Research: Serves as a sophisticated ligand precursor or a model substrate in the development of new catalytic methodologies.
• Fine Chemical Production: Employed in the multistep synthesis of specialty chemicals, flavors, and fragrances where stereochemical control is paramount.
• Academic & Industrial R&D: A valuable tool for chemists exploring novel reaction pathways and the synthesis of natural product analogs.

Basic Information

Product Name	2,2-Dimethyl-Propionic Acid (1R,5R)-6,6-Dimethyl-4-Oxo-Bicyclo[3.1.1]Hept-2-En-2-Ylmethyl Ester
CAS No.	76163-96-7
Molecular Formula	C14H20O3
Molecular Weight	236.31 g/mol
Synonyms	(1R,5R)-6,6-Dimethyl-4-oxobicyclo[3.1.1]hept-2-ene-2-methyl pivalate; Pivalic acid (1R,5R)-6,6-dimethyl-4-oxobicyclo[3.1.1]hept-2-en-2-ylmethyl ester; (-)-Verbenone pivalate; (1R,5R)-2-(Pivaloyloxymethyl)-6,6-dimethylbicyclo[3.1.1]hept-3-en-4-one; Bicyclo[3.1.1]hept-3-en-4-one, 2-(hydroxymethyl)-6,6-dimethyl-, 2-pivalate, (1R,5R)-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.