Description

2-Pinacolateborylindole4 is a specialized organoboron reagent featuring a pinacol-protected boronic ester group on an indole scaffold. This compound is a critical building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation through cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of complex heterocyclic molecules.

Application

• Key intermediate in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl systems.
• Building block for the synthesis of pharmaceutical candidates, particularly those containing functionalized indole cores.
• Precursor in the development of organic electronic materials and advanced polymers.
• Research reagent for methodology development in transition metal-catalyzed processes.
• Used in the synthesis of agrochemicals and fine chemicals requiring specific indole-based architectures.
• Starting material for creating molecular probes and ligands for catalysis.

Basic Information

Product Name	2-Pinacolateborylindole4
CAS No.	76004-81-6
Molecular Formula	C₁₄H₁₈BNO₂
Molecular Weight	243.11 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 2-(Pinacolboranyl)indole; 2-Indoleboronic Acid Pinacol Ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indole; 2-Boron-indole, pinacol ester; 1H-Indole-2-boronic acid, pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2-Pinacolateborylindole4 is manufactured and tested under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. Our products undergo rigorous quality testing, including NMR and HPLC analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.