Description

Butanedioic Acid, Fluoro-, Dimethyl Ester, (S)- (9Ci) is a high-value chiral fluorinated succinate derivative, serving as a critical building block in advanced organic synthesis. Its precise stereochemistry and fluorine substitution make it indispensable for introducing specific molecular frameworks with enhanced biological activity and metabolic stability. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, chiral ligands, and complex intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced, fluorinated pesticides and herbicides where the (S)-configuration imparts specific biological activity.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Research: Employed in the development of specialty polymers and liquid crystals where fluorinated units modify material properties.
• Chemical Biology & Proteomics: Utilized as a building block for activity-based probes and molecular tags to study enzyme function and protein interactions.

Basic Information

Product Name	Butanedioic Acid, Fluoro-, Dimethyl Ester, (S)- (9Ci)
CAS No.	76003-47-9
Molecular Formula	C6H9FO4
Molecular Weight	164.13 g/mol
Synonyms	(S)-2-Fluorobutanedioic Acid Dimethyl Ester; Dimethyl (S)-2-Fluorobutanedioate; (S)-2-Fluorodimethyl Succinate; (S)-Dimethyl 2-Fluorobutanedioate; (S)-Dimethyl 2-Fluorobutanedioate; (S)-2-Fluorobutanedioic Acid 1,4-Dimethyl Ester; (S)-2-Fluorosuccinic Acid Dimethyl Ester; (S)-Dimethyl 2-Fluorosuccinate
EINECS	Contact for details

Quality Control

Our production of Butanedioic Acid, Fluoro-, Dimethyl Ester, (S)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is fully characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.