Description

1,2-Di-o-Hexylglycero-3-(Ethyl Diazomalonamidoethyl Phosphate) is a specialized synthetic intermediate featuring a diazo functional group, making it a valuable precursor for photoaffinity labeling and cross-linking studies in biochemical research. Its core value lies in enabling the covalent attachment of probes to biological targets under controlled light activation, facilitating the study of protein-ligand interactions and enzyme mechanisms. This compound is essential for research and development laboratories in the pharmaceutical, biotechnology, and agrochemical sectors focused on molecular biology, proteomics, and drug discovery.

Application

• Photoaffinity Labeling: A key reagent for covalently tagging proteins, enzymes, or receptors with photolabile probes to study binding sites and interaction networks.
• Bioconjugation & Cross-linking: Used to create stable cross-links between biomolecules for structural analysis, complex stabilization, or the development of diagnostic assays.
• Proteomics Research: Employed in activity-based protein profiling (ABPP) to identify and characterize active enzymes within complex biological samples.
• Drug Discovery Platforms: Serves as a critical building block in developing targeted therapeutics and understanding drug-receptor interactions at the molecular level.
• Material Science Functionalization: Potential use in surface modification and the creation of functionalized polymers with specific biological activity.

Basic Information

Product Name	1,2-Di-o-Hexylglycero-3-(Ethyl Diazomalonamidoethyl Phosphate)
CAS No.	75917-95-2
Molecular Formula	C24H46N3O9P
Molecular Weight	551.61 g/mol
Synonyms	Ethyl 2-diazo-3,3-bis(hexyloxy)-2-[(2-phosphonooxyethyl)carbamoyl]propanoate; Diazomalonamidoethyl Phosphate Derivative; Photoaffinity Labeling Agent 75917-95-2; DGEP; 1,2-Dihexylglyceryl Ethyl Diazomalonamidoethyl Phosphate; Hexyl Glycerol Diazomalonamide Phosphate Ester
EINECS	Contact for details

Quality Control

Our production of 1,2-Di-o-Hexylglycero-3-(Ethyl Diazomalonamidoethyl Phosphate) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with internal quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and decomposition. Allow the container to reach room temperature in a desiccator before opening to prevent moisture condensation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to amber viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.