Description

(3R,3As,4R,6S,9E,11As)-3A,5,6,8,11,11A-Hexahydro-4-Hydroxy-3,6,10-Trimethylcyclodeca[B]Furan-2,7(3H,4H)-Dione is a complex sesquiterpene lactone derivative with a unique fused-ring structure. This compound serves as a critical chiral intermediate and building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams focused on developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Asymmetric Synthesis: Utilized as a sophisticated building block for constructing complex natural product analogs and bioactive molecules.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library development.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of high-value target compounds.
• Reference Standard: Acts as an analytical standard for quality control and method development in API manufacturing.
• Academic & Industrial R&D: Employed in exploratory research for new chemical entities and material science applications.

Basic Information

Product Name	(3R,3As,4R,6S,9E,11As)-3A,5,6,8,11,11A-Hexahydro-4-Hydroxy-3,6,10-Trimethylcyclodeca[B]Furan-2,7(3H,4H)-Dione
CAS No.	75911-35-2
Molecular Formula	C15H20O4
Molecular Weight	264.32 g/mol
Synonyms	Cyclodeca[B]Furan-2,7-dione, 3a,5,6,8,11,11a-hexahydro-4-hydroxy-3,6,10-trimethyl-, (3R,3aR,4R,6S,9E,11aR)-; 4-Hydroxy-3,6,10-trimethyl-3a,5,6,8,11,11a-hexahydrocyclodeca[b]furan-2,7-dione; (3R,3aR,4R,6S,9E,11aR)-4-Hydroxy-3,6,10-trimethyl-3a,5,6,8,11,11a-hexahydrocyclodeca[b]furan-2,7-dione; Sesquiterpene Lactone Derivative; CAS 75911-35-2
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS, to ensure batch-to-batch consistency and identity. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.