Description

cis-Ethyl 4-Hydroxycyclohexanecarboxylate is a versatile chiral building block and ester derivative of 4-hydroxycyclohexanecarboxylic acid. This compound is valued for its unique stereochemistry and functional groups, making it a critical intermediate in sophisticated organic synthesis. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other therapeutic agents requiring specific stereochemistry.
• Liquid Crystal Material Precursor: Used in the research and development of advanced liquid crystal displays (LCDs) and other optoelectronic materials due to its cyclohexane core and ester functionality.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex esters, ligands, and other specialty chemicals in research and pilot-scale production.
• Agrochemical Intermediate: Employed in the development of novel, high-performance herbicides and pesticides where the cis-cyclohexane structure imparts desired biological activity.
• Polymer Modifier: Acts as a monomer or co-monomer in the synthesis of specialty polymers with tailored properties such as flexibility, adhesion, or thermal stability.
• Fragrance and Flavor Chemistry: Utilized as an intermediate for synthesizing specific aroma chemicals and flavor compounds that require the cyclohexane ring structure.

Basic Information

Product Name	cis-Ethyl 4-Hydroxycyclohexanecarboxylate
CAS No.	75877-66-6
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	Ethyl cis-4-hydroxycyclohexanecarboxylate; 4-Hydroxycyclohexanecarboxylic Acid Ethyl Ester, cis-; cis-4-Hydroxycyclohexanecarboxylic Acid Ethyl Ester; (1r,4r)-Ethyl 4-hydroxycyclohexanecarboxylate; Ethyl (1r,4r)-4-hydroxycyclohexanecarboxylate; trans-Ethyl 4-hydroxycyclohexanecarboxylate (common misnomer); 4-Hydroxy-cyclohexanecarboxylic acid ethyl ester; Cyclohexanecarboxylic acid, 4-hydroxy-, ethyl ester, cis-
EINECS	Contact for details

Quality Control

Our cis-Ethyl 4-Hydroxycyclohexanecarboxylate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (cis-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.