Description

5-Fluoro-3-Biphenylacetic Acid is a high-purity fluorinated biphenyl derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a versatile building block for synthesizing complex molecules with enhanced biological activity and metabolic stability. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material science industries, where the introduction of fluorine atoms is a key strategy in molecular design.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for anti-inflammatory and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorinated biphenyl core contributes to efficacy and environmental persistence profiles.
• Liquid Crystal & OLED Material Precursor: Serves as a foundational component in the synthesis of fluorinated organic compounds for electronic displays and lighting applications.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new fluorination methodologies and structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: A starting material for custom chemical synthesis services catering to specialized client projects in life sciences.

Basic Information

Product Name	5-Fluoro-3-Biphenylacetic Acid
CAS No.	75852-54-9
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	[3-(5-Fluorophenyl)phenyl]acetic Acid; 2-[3-(5-Fluorophenyl)phenyl]acetic Acid; 5-Fluoro-[1,1'-biphenyl]-3-acetic Acid; 3'-Fluoro-3-biphenylacetic Acid; 5-Fluoro-3-phenylphenylacetic Acid; 5-Fluoro-m-terphenyl-3'-acetic Acid (related); FBPAA (abbreviation)
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-Biphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting standards for research and production use. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.