Description

1,2,4-Tris(2-Hydroxyethyl)-1,2,4-Triazolidine-3,5-Dione is a specialized heterocyclic compound featuring a triazolidinedione core substituted with three hydroxyethyl groups. This unique structure makes it a valuable intermediate and functional additive in advanced chemical synthesis. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and polymer industries for its reactivity and potential as a building block or cross-linking agent.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a functionalized heterocyclic scaffold.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a cross-linking agent or chain extender in the production of specialty polyurethanes, epoxy resins, and other performance polymers.
• Bioconjugation & Linker Chemistry: Its reactive groups make it suitable for creating chemical linkers in bioconjugation applications for drug delivery systems or diagnostic assays.
• Research & Development: A versatile building block for organic synthesis in academic and industrial research laboratories exploring new chemical entities.
• Cosmetic Ingredient Intermediate: Potential use in synthesizing specialty additives for personal care formulations.

Basic Information

Product Name	1,2,4-Tris(2-Hydroxyethyl)-1,2,4-Triazolidine-3,5-Dione
CAS No.	75797-21-6
Molecular Formula	C9H17N3O5
Molecular Weight	247.25 g/mol
Synonyms	1,2,4-Triazolidine-3,5-dione, 1,2,4-tris(2-hydroxyethyl)-; Tris(2-hydroxyethyl)triazolidinedione; 1,2,4-Tris(2-hydroxyethyl)-1,2,4-triazolidine-3,5-dione; THETD; Glycidaldehyde trimer derivative; N,N',N''-Tris(2-hydroxyethyl)isocyanurate (common misnomer, related structure); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 1,2,4-Tris(2-Hydroxyethyl)-1,2,4-Triazolidine-3,5-Dione is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.