Description

4,4'-Dichloro-3,3',5,5'-Tetrafluoro-1,1'-Biphenyl is a high-purity, multi-halogenated biphenyl derivative of significant interest in advanced organic synthesis. This compound serves as a critical fluorinated and chlorinated building block, enabling the precise construction of complex molecular architectures. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for enhanced bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the tetrafluoro-dichloro substitution pattern can impart unique biological properties.
• Liquid Crystal & OLED Materials: Serves as a fundamental building block for creating fluorinated components in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), contributing to improved electronic and optical characteristics.
• Polymer & Resin Modifier: Incorporated into high-performance polymers, resins, and engineering plastics to enhance thermal stability, chemical resistance, and flame-retardant properties.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the presence of reactive chlorine atoms, facilitating the creation of complex biaryl systems.
• Organic Electronic Materials: Used in the synthesis of semiconductors and charge-transport materials for next-generation electronic devices.

Basic Information

Product Name	4,4'-Dichloro-3,3',5,5'-Tetrafluoro-1,1'-Biphenyl
CAS No.	75795-05-0
Molecular Formula	C12H4Cl2F4
Molecular Weight	295.06 g/mol
Synonyms	3,3',5,5'-Tetrafluoro-4,4'-dichlorobiphenyl; 4,4'-Dichloro-3,3',5,5'-tetrafluorobiphenyl; Biphenyl, 4,4'-dichloro-3,3',5,5'-tetrafluoro-; 1,1'-Biphenyl, 4,4'-dichloro-3,3',5,5'-tetrafluoro-; Tetrafluorodichlorobiphenyl
EINECS	Contact for details

Quality Control

Our 4,4'-Dichloro-3,3',5,5'-Tetrafluoro-1,1'-Biphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical data are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.