Description

Benzene, 1-Bromo-4-(Trimethylsilylcarbonyl)- is a specialized organosilicon and halogenated aromatic compound, identified by CAS No. 75748-11-7. This chemical serves as a versatile building block in advanced organic synthesis, offering unique reactivity for introducing both bromo and trimethylsilylcarbonyl functional groups. It is primarily used by researchers and process chemists in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of complex drug candidates, particularly in cross-coupling reactions like Suzuki or Stille couplings.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Employed in the synthesis of advanced organic materials, including liquid crystals and organic semiconductors.
• Organic Synthesis Reagent: Functions as a protected or masked carboxylic acid equivalent in multi-step synthetic sequences.
• Chemical Research: Utilized in academic and industrial R&D labs for exploring new reaction methodologies and constructing complex molecular architectures.

Basic Information

Item	Details
Product Name	Benzene, 1-Bromo-4-(Trimethylsilylcarbonyl)-
CAS No.	75748-11-7
Molecular Formula	C10H13BrOSi
Molecular Weight	257.20 g/mol
Synonyms	1-Bromo-4-(trimethylsilylcarbonyl)benzene; 4-Bromobenzoyltrimethylsilane; p-Bromobenzoyltrimethylsilane; (4-Bromobenzoyl)trimethylsilane; Trimethyl(4-bromobenzoyl)silane; Benzene, 1-bromo-4-[(trimethylsilyl)carbonyl]-; 4-Bromophenyl trimethylsilyl ketone
EINECS	Contact for details

Quality Control

Our Benzene, 1-Bromo-4-(Trimethylsilylcarbonyl)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.