Description

2-Methylbutanoic Acid [[(3Ar,4R,6Z,10Z,11Ar)-10-Acetoxymethyl-2,3,3A,4,5,8,9,11A-Octahydro-4-Hydroxy-3-Methylene-2-Oxocyclodeca[B]Furan-6-Yl]Methyl] Ester is a complex, high-purity synthetic ester with a unique fused-ring structure. This compound is valued for its role as a key chiral intermediate in advanced organic synthesis, particularly for the construction of intricate molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex drug candidates, especially those with macrocyclic or polycyclic frameworks.
• Advanced Organic Synthesis: Used in research and development for constructing chiral, non-racemic molecules requiring specific stereochemistry.
• Fine Chemical Production: Acts as a precursor for specialty chemicals, including fragrances, flavors, and advanced material monomers where precise structure is paramount.
• Academic & Industrial Research: A valuable reagent for methodological studies in total synthesis, catalysis, and stereoselective reactions.
• Bioconjugate Chemistry: Potential use in the development of linker molecules or payloads for antibody-drug conjugates (ADCs) due to its functionalizable ester and hydroxyl groups.

Basic Information

Product Name	2-Methylbutanoic Acid [[(3Ar,4R,6Z,10Z,11Ar)-10-Acetoxymethyl-2,3,3A,4,5,8,9,11A-Octahydro-4-Hydroxy-3-Methylene-2-Oxocyclodeca[B]Furan-6-Yl]Methyl] Ester
CAS No.	75683-60-2
Molecular Formula	C23H32O7
Molecular Weight	420.50 g/mol
Synonyms	[(3aR,4R,6Z,10Z,11aR)-10-(Acetoxymethyl)-2,3,3a,4,5,8,9,11a-octahydro-4-hydroxy-3-methylene-2-oxocyclodeca[b]furan-6-yl]methyl 2-methylbutanoate; 2-Methylbutyric Acid [[(3Ar,4R,6Z,10Z,11Ar)-10-Acetoxymethyl-2,3,3A,4,5,8,9,11A-Octahydro-4-Hydroxy-3-Methylene-2-Oxocyclodeca[B]Furan-6-Yl]Methyl] Ester; (3aR,4R,6Z,10Z,11aR)-6-[[(2-Methylbutanoyl)oxy]methyl]-10-(acetoxymethyl)-3a,4,5,8,9,11a-hexahydro-4-hydroxy-3-methylidene-2H-cyclodeca[b]furan-2-one
EINECS	Contact for details

Quality Control

Our 2-Methylbutanoic Acid [[(3Ar,4R,6Z,10Z,11Ar)-10-Acetoxymethyl-2,3,3A,4,5,8,9,11A-Octahydro-4-Hydroxy-3-Methylene-2-Oxocyclodeca[B]Furan-6-Yl]Methyl] Ester is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC and NMR, to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and hydrolysis; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.