Description

20-Deoxyingenol 3-Angelate is a specific, high-purity diterpenoid ester of significant interest in advanced pharmaceutical and biochemical research. This compound matters as a key intermediate and reference standard for the development of novel therapeutic agents, particularly in oncology and anti-inflammatory studies. Research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers need this material for its role in probing biological pathways and synthesizing more complex bioactive molecules.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control and analytical method development in drug discovery pipelines.
• Biochemical Research: Serves as a crucial tool compound for studying protein kinase C (PKC) modulation and related cellular signaling mechanisms.
• Precursor for Drug Synthesis: Acts as a sophisticated synthetic intermediate for the preparation of ingenol and other diterpenoid-based pharmaceutical candidates.
• Natural Product Isolation & Analysis: Employed as a benchmark in the isolation, identification, and quantification of related compounds from plant extracts like those from the Euphorbia genus.
• Academic & Contract Research: Essential for universities and CROs conducting fundamental research on tumor promotion, cell proliferation, and apoptosis.

Basic Information

Product Name	20-Deoxyingenol 3-Angelate
CAS No.	75567-38-3
Molecular Formula	C25H34O6
Molecular Weight	430.53 g/mol
Synonyms	20-Deoxyingenol angelate; Ingenol 20-deoxy-3-angelate; 3β-Angeloyloxy-9α,13α-epoxy-7α-hydroxy-1α,6α,8β-trimethyl-4α,5α,6β,7β,8α,9β,10α,11α-dodecahydro-2H-cyclodeca[a]naphthalen-2-one; 20-Deoxy-ing-enol-3-angelate; 3-Angeloyloxy-20-deoxyingenol; (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6,9,10,10a-Hexahydro-1a,2,5,7,8,8a-hexamethyl-9-(1-methylethenyl)-1H-naphtho[1,8a-b]oxireno[4,5]cyclopenta[1,2-d]furan-1,6(2H)-dione 2-angelate
EINECS	Contact for details

Quality Control

Our 20-Deoxyingenol 3-Angelate is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. Identity, purity, and impurity profiles are verified using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.